TR Gowrishankar

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Publications

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Weaver Group
MIT
Univ of Chicago
George Mason Univ
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Last Modified:
Jan 15, 2009

tgowrish@mit.edu

Publications

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Tramsdermal drug delivery by localized intervention: field-confined skin electroporation and dermal microscissioning
TR Gowrishankar, TO Herndon, JC Weaver
IEEE Eng Med Biol 28(1):55-63 Jan-Feb 2009.

Towards Solid Tumor Treatment by Irreversible Electroporation: Intrinsic Redistribution of Fields and Currents in Tissue
Axel T. Esser, Kyle C. Smith, Thiruvallur R. Gowrishankar, James C. Weaver
Tech. Cancer Res. Treat. 6(4):261-274, Aug 2007.

Controlled nail trephination for subungual hematoma
SA Salter, DH Ciocon, TR Gowrishankar, AB Kimball
The American Journal of Emergency Medicine, 24:875-7, 2006.

Electrical behavior and pore accumulation in a multicellular model for conventional and supra-electroporation
T. R. Gowrishankar and James C. Weaver
Biochem. Biophys. Res. Comm., 349:643-53, 2006

Skin Heating and Injury by Prolonged Millimeter-Wave Exposure: Theory Based on a Skin Model Coupled to a Whole Body Model and Local Biochemical Release From Cells at Supraphysiologic Temperatures
Stewart, D.A., Gowrishankar, T.R., Weaver, J.C.
IEEE Trans Plasma Sci, 34(4, part 2):1480-1493, 2006

Membrane electroporation: The absolute rate equation and nanosecond time scale pore creation
Zlatko Vasilkoski, Axel T. Esser, T. R. Gowrishankar, and James C. Weaver
Phys Rev E, 74, 021904, 2006.

How low should you go: a novel device for trephination
D Ciocon, TR Gowrishankar, TO Herndon, AB Kimball
Derm Surg 2006 Jun; 32(6):828-33.

The spatially distributed, dynamic transmembrane voltage of cells and organelles due to 10~ns pulses: meshed transport networks
Kyle C. Smith, T. R. Gowrishankar, Axel T. Esser, Donald A. Stewart and James C. Weaver
IEEE Trans Plasma Sci 34(4):1394-1404, 2006.

Microdosimetry for conventional and supra-electroporation in cells with organelles
TR Gowrishankar, AT Esser, Z Vasilkoski, KC Smith, JC Weaver
Biochem. Biophys. Res. Commun., 341(4):1266-76, Mar 24 2006.

Three dimensional transport lattice model for describing action potentials in axons stimulated by external electrodes
DA Stewart, TR Gowrishankar, JC Weaver
Bioelectrochemistry 69:88-93 2006

Model of a Confined Spherical Cell in Uniform and Heterogeneous Applied Electric Fields
TR Gowrishankar, DA Stewart, JC Weaver
Bioelectrochemistry 68:185-194 2005

Cylindrical Cell Membranes in Uniform Applied Electric Fields: Validation of a Transport Lattice Method
DA Stewart Jr, TR Gowrishankar, KC Smith, JC Weaver
IEEE Transactions on Biomedical Engineering, 52(10):1643-1653, Oct. 2005

Screening soft materials for their effect on skin barrier function by high throughput experimentation
JM Newsam, D King-Smith, A Jain, P Karande, I Feygin, J Burbaum, TR Gowrishankar, M Sergeeva, S Mitragotri
J Mat Chem, 10:1039/b416210b, 2005

Transport lattice models of heat transport in skin with spatially heterogeneous, temperature-dependent perfusion
TR Gowrishankar, Donald A Stewart, Gregory T Martin, and James C Weaver
BioMedical Engineering OnLine, 3:4. 2004

Transport lattice approach to describing cell electroporation: use of a local asymptotic model
Stewart DA Jr., Gowrishankar TR, Weaver JC
IEEE Transactions on Plasma Science 32 (4): 1696-1708 AUG 2004

Electroporation of a lipid bilayer as a chemical reaction
Bier M, Gowrishankar TR, Chen W, Lee RC
Bioelectromagnetics 25 (8): 634-637 DEC 2004

Electroporation of a multicellular system: asymptotic model analysis
T. R. Gowrishankar, Chip Stewart, and James C. Weaver
Proc. 26th Ann. Int. Conf. IEEE EMBS, San Francisco, CA, USA, Sep. 1-5, 2004. pp. 5444-5446

Transdermal microconduits by microscission for drug delivery and sample acquisition
Terry O Herndon, Salvador Gonzalez, TR Gowrishankar, R Rox Anderson and James C Weaver
BMC Medicine 2:12. 2004

An approach to electrical modeling of single and multiple cells
Gowrishankar TR, Weaver JC
Proc Natl Acad Sci USA 100(6): 3203-3208 Mar 18, 2003

Resealing dynamics of a cell membrane after electroporation
Bier M, Chen W, Gowrishankar TR, Astumian RD, Lee RC
Physical Review E 66 (6): Art. No. 062905 Part 1, DEC 2002

Microfabrication of individual 200 um diameter transdermal microconduits using high voltage pulsing in salicylic acid and benzoic acid
Ilic L, Gowrishankar TR, Vaughan TE, Herndon TO, Weaver JC
J Inv. Derm. 116(1): 40-49 Jan 2001

Spatially constrained skin electroporation with sodium thiosulfate and urea creates transdermal microconduits
Ilic L, Gowrishankar TR, Vaughan TE, Herndon TO, Weaver JC
Journal of Controlled Release 61: (1-2) 185-202 AUG 27 1999

Changes in skin structure and electrical properties following high voltage exposure
Gowrishankar TR, Pliquett U, Weaver JC
Ann NY Acad Sci 888: 183-194 1999

Dynamics of membrane sealing in transient electropermeabilization of skeletal muscle membranes
Gowrishankar TR, Pliquett U, Lee RC
Ann NY Acad Sci 888: 195-210 1999

Spatially constrained localized transport regions due to skin electroporation
Gowrishankar TR, Herndon TO, Vaughan TE, Weaver JC
Journal of Controlled Release 60: (1) 101-110 JUN 28 1999

Recent advances in skin electroporation: mechanism and efficacy
Weaver JC, UF Pliquett, TE Zewert, R Vanbever, TO Herndon, TR Gowrishankar, T Chen, MR Prausnitz, TE Vaughan, Y Chizmadzhev, V Preat, R Langer
In Electricity and Magnetism in Biology and Medicine, F Bersani, Ed., Plenum Press, New York, pp 149-152, 1999

Non-linear microscale alterations in membrane transport by electropermeabilization
Gowrishankar TR, W Chen, RC Lee
Ann NY Acad Sci 858: 205-216 1998

The 1996 Lindberg Award. Calcium antagonists alter cell shape and induce procollagenase synthesis in keloid and normal human dermal fibroblasts
Doong H; Dissanayake S; Gowrishankar TR; LaBarbera MC; Lee RC
J Burn Care Rehabil (HLK), 1996 Nov-Dec; 17 (6 Pt 1): 497- 514

Characterization of non-linear electrical behavior of lipid bilayer of cell membranes
Gowrishankar TR, W Chen, RC Lee
Proc. IEEE Eng. Med. Biol. Soc. Conf. 1995

3-D reconstruction of a skeletal muscle cell from optical sections
Gowrishankar TR, RC Lee, C-T Chen
Proc. SPIE Int. Conf. Biomed. Image Processing, San Jose, CA 1905:152-157 1993

Cell shape dependent rectification of surface receptor transport in a sinusoidal A.C. electric field
Lee RC, Gowrishankar TR, RO Basch, P Patel, DE Golan
Biophys. J. 64:44-57, 1993