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Molecular change due to biomagnetic stimulation and transient magnetic fields: mechanical interference constraints on possible effects by cell membrane pore creation via magnetic particles
Vaughan TE, Weaver JC
Bioelectrochem. Bioenerg. 46: (1) 121-128 Aug 1998

Possible human health hazards due to biomagnetic stimulation and other transient magnetic fields are assessed theoretically by considering magnetic field pulses that might create metastable cell membrane pores via interaction with membrane-attached magnetic particles. Such pores could lead to molecular changes sufficient to alter biochemical processes by admitting extracellular molecules that ordinarily cannot enter the cytosol, and can generate a molecular influx burst which satisfies a molecular shot noise constraint. Sources of competing molecular changes are considered. Possible pore creation due to normally encountered accelerations is usually insignificant. However, mechanical interference arising from membrane openings by tissue strain in naturally moving tissues is expected to lead to more severe competing molecular changes for most cells; only cells of bone-encased tissues (marrow and brain) remain as candidates. Such mechanical interference is also relevant to any other biophysical mechanism that couples molecular change to electric or magnetic fields by cellular deformation.