Gel microdrop technology for rapid isolation of rare and
high producer cells.
Weaver JC; McGrath P; Adams S Nat Med (CG5), 1997 May; 3 (5): 583-5
Secreted proteins are a therapeutic cornerstone of the
biotechnology industry, and numerous recombinant products,
including human growth hormone, human erythropoietin and
granulocyte-colony stimulating factor, are now widely
prescribed. In addition to bioprocessing applications, GMD
technology should benefit the emerging fields of cellular
and gene therapy. The ability to assess rapidly and
precisely the productivity of cells for ex vivo cell
screening and expansion is a unique approach with numerous
research and therapeutic uses.